Understanding the Impact of Menopause on Premenstrual Dysphoric Disorder

What is PMDD?

Premenstrual Dysphoric Disorder (PMDD) is a severe and chronic medical condition that affects individuals during the luteal phase of their menstrual cycle—the two weeks leading up to menstruation. It is often described as an intensified form of premenstrual syndrome (PMS), but the symptoms of PMDD are far more disruptive and debilitating, impacting emotional, mental, and physical well-being.

Why does it get worse during the perimenopause?

During perimenopause—the years leading up to menopause—oestrogen and progesterone levels fluctuate more dramatically and unpredictably than at any other time in a person’s reproductive life. For individuals with PMDD, who are already highly sensitive to hormonal changes, this can intensify both emotional and physical symptoms.

Interestingly, for some people, PMDD may first emerge during perimenopause, even if they never experienced it earlier in life. This is due to the sudden onset of hormonal volatility that can trigger symptoms in previously unaffected individuals.

What are the treatment options?

Navigating PMDD is already challenging—but when perimenopause enters the picture, it can feel like the rules suddenly change. The hormonal chaos of this life stage can intensify symptoms, but the good news is: you’re not powerless. There are effective strategies—both medical and holistic—that can help you regain control and find relief.

💊 1. Medical Treatments

Hormonal therapies aim to stabilize the fluctuations that trigger PMDD symptoms:

• Combined oral contraceptives: Can suppress ovulation and regulate hormone levels.

• GnRH agonists: Temporarily induce a menopausal state to halt hormonal cycling (often used short-term with add-back therapy).

• Hormone Replacement Therapy (HRT): For those already in late perimenopause, HRT may help ease both PMDD and menopausal symptoms.

Antidepressants (SSRIs) are also commonly prescribed:

• Taken daily or just during the luteal phase

• Can significantly reduce mood-related symptoms like anxiety, irritability, and depression (1)

🌿 2. Lifestyle & Holistic Approaches

While not a cure, these can make a meaningful difference:

• Nutrition: A diet rich in whole foods, omega-3s, and low in sugar and caffeine can help stabilize mood and energy.

• Exercise: Regular movement—especially aerobic activity—can boost endorphins and reduce stress.

• Sleep hygiene: Prioritize consistent, quality sleep to support emotional regulation.

• Mindfulness & stress reduction: Practices like yoga, meditation, or CBT can help manage emotional reactivity (2).

📓 3. Track Your Cycle & Symptoms

Use a journal or app to:

• Identify patterns in your symptoms

• Communicate more clearly with healthcare providers

• Anticipate flare-ups and plan self-care accordingly

🤝 4. Seek Support

You don’t have to go through this alone:

• Therapists who specialize in hormonal mood disorders can offer coping tools (3)

• Support groups (online or in person) can provide validation and community

• Partner and family education can help your loved ones understand what you’re experiencing (4)

💬 Final Thought

PMDD during perimenopause can feel like a double storm—but with the right tools and support, it’s possible to weather it with strength and clarity. You deserve to feel well, heard, and empowered.

References:

  1. https://cks.nice.org.uk/topics/premenstrual-syndrome/

  2. The Period Repair Manual by Lara Briden

  3. https://www.mind.org.uk/information-support/types-of-mental-health-problems/premenstrual-dysphoric-disorder-pmdd/treatment-for-pmdd/

  4. https://www.iapmd.org/support

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Book Club Pick for July: “The Definitive Guide to the Perimenopause and Menopause” by Dr Louise Newson